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Find out the latest news and events from the supplements industry.
NXT USA
Blending botanicals with science: NXT USA’s portfolio at Expo West 2026
Highlighted ingredients include Xeya Modern Shatarvi, BluNAD Booster, Digexin, and TamaFlex. The portfolio is positioned around four validation pillars providing clinical data for natural ingredients.
NXT USA
The Tragedy of the Commons and Why Your Industry’s Integrity Matters
“There are companies really trying hard to bring efficacious, clinically validated products to market,” says NXT USA's Managing Director Eric Anderson.
Xeya Shatavari
Shatavari extract improves PCOS symptoms and regulates cycle
Women drive supplement adoption yet face persistent care gaps — high symptom burden, long diagnosis journeys and limited solutions that truly fit their lives. Brands that deliver clinically supported relief at low doses earn trust, improve adherence and drive repeat purchases.
BluNAD Booster
Longevity nutraceuticals are coming of age
The new calculus in NAD+ powered cellular wellness is that it’s not just how much NAD+ you produce but how much you keep.
Xeya Shatavari
Xeya Shatavari Supports Hormonal Balance, Insulin Sensitivity in Women with PCOS: Study
Over 12 weeks, participants saw improved measures of ovarian health, hormonal balance, metabolism, physical improvements, and menstrual regularity.
Xeya Shatavari
NXT USA study shows Xeya Modern Shatavari helps with PCOS symptoms
For finished product brands, Xeya offers a differentiated, clinically substantiated ingredient that can anchor PCOS and menstrual health formulas, women’s metabolic and hormone-balance concepts.
Xeya Shatavari
New study shows Xeya to be a "hormonal adaptogen"
The PCOS study, taken along with earlier research done with perimenopausal women, bolsters the brand’s emerging concept of Xeya Modern Shatavari as a “hormonal adaptogen.”
Xeya Shatavari
NXT USA’s shatavari extract boosts women’s ovarian function, metabolism and hormonal balance
Xeya Modern Shatavari improves ovarian morphology in women with PCOS by reducing cyst size, follicle count, and overall ovarian volume.
Xeya Shatavari
Standardized shatavari root extract demonstrates ovarian, hormonal, and metabolic benefits in women with PCOS
The study suggests the supplement as a promising holistic management strategy for PCOS, targeting both endocrine and metabolic factors.
BluNAD Booster
Research update: Improved NAD+ Levels, Mitochondrial Health & Physical Performance
”The market has been waiting for an NAD+ solution that goes beyond precursors alone. BluNADBooster represents a next-generation approach, one that strengthens the body’s ability to generate —and maintain—healthy NAD+ that declines with age."
From Hype to Proof: How to redefine supplement science and innovation
The future of nutraceuticals lies at the intersection where validated science meets human relevance, and where brands don't just sell wellness, but prove it.
Supplement Shorts: science-supported product launches and claims
NXT USA announced third-party validation of its 7-day digestive regularity claims for Digexin, a proprietary blend of okra and ashwagandha extracts. Regulatory compliance firm REJIMUS verified the claims by evaluating clinical trials on Digexin.
Botanical NAD Booster Improves NAD+ Production, Mitochondrial Function, and Various Health Measures
The polyphenol-rich BluNADBooster was found to have greater effects in a head-to-head comparison against nicotinamide riboside (NR).
NXT USA’s Digexin Receives Third-Party Endorsement for Digestive Regularity Claims
The ingredient's claim of seven-day efficacy was validated by Rejimus, Inc., a regulatory compliance firm specializing in dietary supplement marketing language.
NXT USA’s Digexin digestive health claims backed by third-party validation
NXT USA has received independent third-party testing to back “compliant, ready-to-use claim language” for finished products.
Finished products, unfinished science
Nutrition Business Journal’s October 2025 “Science & Innovation” issue investigates supplement brands that rely on ingredient science to sell their supplements. NXT USA executive director Eric Anderson says NXT’s quality ingredient research wins contracts.
New study poised to shift how the nutraceutical industry thinks about NAD+ support
Researchers have uncovered that the botanical complex BluNADBooster outperformed the category’s benchmark precursor ingredient, nicotinamide riboside — commercially sold as TruNiagen — in multiple healthy-ageing domains.
Digexin Relieves Digestive Complaints Associated with GLP-1 RA Use: Study
Clinical study participants taking GLP-1 receptor agonists reported fewer gastrointestinal side effects after supplementing with the blend of okra and ashwagandha extracts.
NXT USA's polyphenol blend outperforms NAD+ precursor for healthy aging
Combining BluNADBooster and NR produced the greatest increase in NAD+ levels, along with improved cognition, physical performance, and quality of life.
NXT USA’s proprietary Digexin formula relieves upset gut in GLP-1 patients
Research indicates that NXT USA’s proprietary formulation Digexin addresses various types of gastrointestinal (GI) issues in adults prescribed GLP-1 receptor agonist therapy.
Xeya Modern Shatavari from NXT USA featured at SSG
New ingredients and clinical research supporting women’s health highlighted at supplier booths and educational sessions during SupplySide Global 2025
Digexin gains third-party validation for 7-day digestive regularity claims in the US market
NXT USA’s patented herbal blend has received independent substantiation confirming its fast-acting digestive health claims, giving US supplement brands compliant, clinically backed marketing language.
Xeya Modern Shatavari from NXT USA Sets Benchmark for Women’s Hormonal Health
Two human clinical studies demonstrate benefits of low-dose, high-potency shatavari.
Xeya® Shatavari (50mg): The Queen of Ayurveda Meets Modern Science
From breakthrough clinical evidence to mechanisms of hormonal support, Xeya Modern Shatavari from NXT USA is next-generation.
Pillars and proof
The NXT USA “Four Pillars of Validation” provides claims that can build a supplement brand. These four study design elements convince brands we have done our homework, that the ingredient can be trusted, that their consumers can trust the product to change lives.
GLP-1 support takes over SupplySide Global 2025
GLP-1 support ingredients took SupplySide Global 2025 by storm, with ingredient manufacturers like NXT USA showcasing ingredients that support GLP-1 users.
Digexin digestive regularity claims confirmed by third-party regulatory compliance firm
REJIMUS's validation allows brands to market Digexin with strong, compliant claims, enhancing consumer trust and loyalty.
The skinny on success: Why pharma's weight-loss winners need nutritional backup
Digestive health doesn't have to be dirty. In this digital magazine roundup, Digexin is highlighted as a key ingredient to ease unpleasant side effects with GLP-1 medications.
New menopause study boosts research backing for shatavari
A study on a new-to-the-market proprietary shatavari extract has validated the herb’s benefits for menopausal women.
New study shows Xeya Modern Shatavari eases perimenopause complaints
The fast-growing perimenopause supplement category has received strong validation from a comprehensive study demonstrating the benefits fo the Xeya Ayurvedic herb shatavari (Asparagus racemosus).
Clinical study finds shatavari extract reduces hot flashes and night sweats in perimenopausal women
The study tested two doses of the asparagus racemosus root extract Xeya Modern Shatavari for its effect on symptom reduction and quality of life.
RCT supports shatavari benefits for perimenopausal women
Supplementation with Xeya Modern Shatavari may decrease hot flashes, fatigue and sleep disturbances for perimenopausal women.
Clinical trial finds Shatavari extract Xeya improves quality of life for women with perimenopausal symptoms
NXT USA’s branded ingredient, Xeya Modern Shatavari, has been clinically shown to ease key symptoms in perimenopausal women.
NXT USA’s shatavari solution steps into the perimenopause space
Shatavari (Asparagus racemosus), a plant known as the “queen of Ayurveda,” has been validated in a recent clinical trial.
Cortisol Gut: A women’s health alert
The International Science & Health Foundation is supporting the Cortisol Gut Project. Its mission is to educate that stress affects everyone, but women are particularly vulnerable to the gut-disrupting effects of cortisol. Hormonal changes during perimenopause and menopause can amplify stress responses, leading to digestive discomfort and mood swings.
Tylenol expands into supplement space with joint health product
The makers of Tylenol have launched Proactive Support, a dietary supplement specifically designed to promote joint comfort and mobility.
Tylenol-branded supplements launch based on Ayurvedic joint combo
TamaFlex is a patented combination of tamarind seed and turmeric extracts that has studies showing joint pain relief in as little as five days.
Tylenol Maker Debuts Herbal Supplement Line for Muscle and Joint Health
Muscle & Joint and Muscle & Joint + Stress formulas feature TamaFlex, shown to improve joint comfort, flexibility and function in as early as five days.
Innovation and more research could revive lagging growth in joint health sector
Fast-acting ingredients like TamaFlex show clinical results in just five days, revitalizing the joint health market beyond current $2.25 billion.
Tylenol enters supplement category space with proactive joint care product
Tylenol expanded into the supplement category with the launch of Proactive Support, a drug-free supplement which hopes to offer joint care support.
Tylenol intros Proactive Support to aid in joint comfort, mobility
The company has tapped actress and comedian Molly Shannon to promote the launch of Proactive Support From the Makers of Tylenol.
Tylenol Has Launched Its First Supplement to Support Muscle and Joint Health
Proactive Support contains a blend of turmeric and tamarind, and does not contain acetaminophen, the company said.
TYLENOL® Expands Expertise to Proactive Joint Care with Launch into the Supplement Category
From relief to routine: Proactive Support from the Makers of TYLENOL® delivers clinically backed ingredients that provide effective, drug-free joint support.
Kenvue launches Proactive Support supplement for joint mobility
Proactive Support, developed under the TYLENOL brand, is informed by decades of scientific expertise and addresses the need for drug-free joint support.
Across the Nutraverse: Tylenol’s new joint health supplement
Last week’s big news included Tylenol launching joint health dietary supplement, creatine RTD progress, Thai Union’s new tuna-derived marine collagen.
NXT-USA launches Xeya Shatavari for women’s health
If ashwagandha is the King of Ayurveda, then shatavari is the Queen, Eric Anderson, managing director of NXT USA, told NutraIngredients about the company’s new Xeya-branded ingredient to support women’s hormonal health.
5 new innovative microbiome ingredients
The microbiome is the next new frontier in human health. These new ingredient launches showcase the diverse ways of supporting microbiome health which, in turn, improves health in various ways.
Todd Runestad joins NXT USA as Chief Storytelling Officer
The well-renowned editor and content director has "jumped ship" after 27 years with SupplySide and New Hope Network. As the brand's new Chief Storytelling Officer, Todd will be responsible for guiding NXT USA's overall tone of voice, while also contributing to the brand's public relations and marketing efforts.
Natural Products Expo West 2025: what’s new in the nutraceutical space?
NXT USA’s Xeya Shatavari: A reimagined Ayurvedic ingredient, Xeya Shatavari is designed to support women’s health by offering hormonal management at any life stage. From menstruation to menopause, the nutraceutical is designed to help women feel their best.
NXT USA launches Ayurvedic women's health ingredient, Xeya Shatavari, at Expo West
The health ingredient company's Ayurvedic Shatavari ingredient has been proven to promote hormonal balance, supporting women in menstruation, as well as the menopause.
Study reveals the key role of mitochondria as cellular NAD buffers during cellular ageing
The mitochondria act as a cellular NAD buffer, helping the cell to maintain NAD levels during stress and ensuring that key metabolic processes can still go ahead.
A novel study published in Nature Metabolism has revealed the key role that the mitochondria play in regulating NAD levels during cellular stress and/or ageing.
Newly discovered mechanism sheds light upon aging
In the centre of this new discovery stands a molecule called NAD, or Nicotinamide Adenine Dinucleotide.
Professor Mathias Ziegler from the Department of Biomedicine (UiB), who led the international team of researchers behind the new study, explains its significance.
NXT USA Receives Non-GMO Project Verification
NXT USA has achieved Non-GMO Project Verification for its Digexin and TamaFlex flagship products.
NXT USA Achieves Non-GMO Project Verification for Digexin, TamaFlex
Digexin is a botanical ingredient designed to support digestive regularity and wellness, and TamaFlex is a botanical designed for joint health.
New Human Study Confirms Digexin’s® Regularity and Mood Benefits
NXT USA is thrilled to announce the publication of new human clinical trial in the Journal of the American Nutrition Association. The article, “A novel herbal composition alleviates functional constipation, reduces gastrointestinal transit time, and improves bowel function in adults: A double-blind, randomized clinical study,” showcases Digexin®'s benefits for digestive health and mood support.
Address the stress, improve the gut’: Ashwagandha-okra blend offers novel approach to address digestive health
With new product launches in multiple countries and a newly published review of the science to date, Digexin
NXT USA publishes a review on its gut health
The publication depicts how the functional ingredient can support gut health through the brain
NXT USA partners with Infinity Pharma to launch Digexin in Brazil under the brand name of Motility
NXT USA (Edison, NJ) has announced the launch of its Digexin ingredient in Brazil under the brand name Motility in partnership with Infinity Pharma Brazil.
NXT USA Launches Digexin in Brazil Under Brand Name Motility
NXT USA has announced the launch of Digexin under the brand name Motility in Brazil, in partnership with healthcare product company Infinity Pharma Brazil.
NXT USA debuts gut health ingredient Motility in Brazil
The launch of this gut health-boosting winter cherry root and okra pod nutraceutical in Brazil expands the company's global footprint and brings a digestive wellness offering to the Brazilian market.
NXT USA's TamaFlex receives stamp of approval in Korea as a functional food ingredient
The joint health solution has now been officially approved as a Health Functional Food Ingredient by the MFDS, which is awarded to ingredients with clinical backing and proven efficacy.
Digexin Wins Ingredient Idol! Watch Eric Anderson, Managing Director of NXT USA, in an interview about this prestigious recognition.
Botanical Complex Supports Joint Health Efficacy in Five Days
NXT USA’s TamaFlex improved joint comfort, function, aerobic capacity, and lower body strength of participants significantly, with biomarkers suggesting change.
Digestive Health
One of the fastest growing markets for functional foods and supplements, gut health has caught the attention of many companies and consumers. In this section we’ve compiled all of the latest information on market trends, health statistics, regulations and formulation developments.
Ashwagandha-okra mix shows benefits for digestive regularity, sleep, mood
Supplementation with a proprietary blend of standardized ashwagandha and okra extracts may improve regularity, speed of transit, physical comfort and mental health, says a new randomized, double-blind, placebo-controlled study.
NXT USA’s Digexin blend improves digestive health and mood, new research finds
The results of a recent double-blind, randomized clinical study show that Digexin alleviates functional constipation, reduces gastrointestinal (GI) transit time and improves bowel function, quality of life and mental health.
11 suppliers we’ll fly across the pond to see at Vitafoods
Vitafoods is the tinier, tonier European mashup of Natural Products Expo West and SupplySide West. Here’s the leading suppliers vying for the EU market.
Innovative Science: Tapping Into the Nutrition Connection of the Gut-Brain Axis for Health
Functional gastrointestinal disorders (FGID) impact 40 percent of the global population.1 FGID are a group of disorders with no identified etiology characterized by chronic gastrointestinal (GI) symptoms including abdominal pain, dysphagia, dyspepsia, diarrhea, constipation and bloating.
Brain to Gut Benefits: A Promising Approach for Digestive Health & Regularity
Struggling with constipation? You're not alone. Over 15% of adults worldwide face this digestive issue, impacting more than just digestion - it affects mood, sleep, and social life. Recent research highlights a herbal solution, Digexin, blending ashwagandha and okra extracts. In studies, participants experienced improved regularity, mood, and sleep quality within just 14 days.
Botanical Complex Supports Joint Health Efficacy in Five Days
NXT USA’s TamaFlex improved joint comfort, function, aerobic capacity, and lower body strength of participants significantly, with biomarkers suggesting change.
Digexin wins Ingredient Idol Award for microbiome contributions at SupplySide West!
Digexin boosts serotonin production for better mood and faster digestion. Two clinical studies confirm its effectiveness, with results published in the Journal of Ethnopharmacology in September 2023.
Ashwaganda-Okra mix shows bowel health benefits in proof-of-concept clinical trial
A study in the Journal of Ethnopharmacology found that Digexin, a blend of ashwagandha and okra extracts, relieves constipation and improves quality of life.
Study Backs NXT's constipation relief ingredient
A recent study published in the Journal of Ethnopharmacology supports the effectiveness of Digexin in alleviating constipation and boosting moods. Constipation is a common gastrointestinal issue that can impact our social lives and overall well-being. The study highlights how Digexin can make a difference in this regard.
Clinical trial supports TamaFlex joint health benefits
Improved joint comfort and function, aerobic capacity, and lower body strength was found in people with mild to moderate knee osteoarthritis, says a new study.
Clinical trial supports TamaFlex joint health benefits
A combination of standardized extracts of tamarind seeds and turmeric may improve joint comfort and function, aerobic capacity, and lower body strength in people with mild to moderate knee osteoarthritis, says a new study.
NXT USA's joint comfort supplement backed by third clinical trial
NXT USA published a new human clinical study confirming the joint and physical benefits of TamaFlex. The study, featured in Food and Nutrition Research 67 (2023), reveals that TamaFlex improved participants' joint comfort, function, aerobic capacity, and lower body strength.
The Better Way to Fight Joint Discomfort with Eric Anderson from TamaFlex
In this exciting episode of The NatureCity Podcast, Eric Anderson discusses his groundbreaking joint health innovation, Tamaflex. Watch the podcast to discover the potential of Tamaflex, one of the most significant joint health ingredient in years.
The real anti-aging solution is health span
Insider content director Todd Runestad sits down with Eric Anderson, managing director of NXT-USA to discuss the larger healthy aging opportunity, with a focus on new and novel joint-health ingredients that can bring about relief well within that first supplement bottle.
Shanghai Freemen and NXT USA to launch new digestive health ingredients at SupplySide West
NXT USA and Shanghai Nutra to launch Digexin, a new digestive health ingredient at SupplySide West October 4, 2022. Digexin is supported by a double-blind, placebo-controlled human study, pending publication, to support digestive health and enhance mood.
TamaFlex may support joint health in horses, says a recent study
A recent study published in Veterinary Medicine Science1, found that a botanical formulation containing Tamarindus indica seed extract and Curcuma longa rhizome extract, called TamaFlex, the flagship ingredient of NXT USA, may support joint function in horses.
TamaFlex may support joint health in horses, says recent study
The extract helped improve lameness scores and inflammatory biomarkers in horses.
Joint health ingredient maker says market overdue for new product backed by solid data
The developer of a new ingredient called TamaFlex said its synergistic pairing of Ayurvedic constituents will help breathe life into the somnolescent joint health category.
The new natural plant-based ingredient for a lifetime of joint health
Joint health isn't just for aging consumers. Nearly one in three people aged 18 to 64 either have doctor-diagnosed arthritis and/or report joint discomfort symptoms. That's why it's important for all adults to actively support and maintain their joint health.
The new natural plant-based ingredient for a lifetime of joint health
New plant-based joint supplement delivers fast-acting and long-lasting benefits now shown effective in 5 days
Opportunities in the joint health market
Surprisingly, the fastest-growing group of individuals having knee replacement surgery is not the retirement-age crowd, but those under 50 years old.
New data proves that Tamaflex can be effective in joint health in horses
Millions of horses are suffering from joint pain and disability. Eric Anderson from NXT-USA believes that equines need a new, effective supplement and Tamaflex is the answer.
Opportunities in the joint health market
The joint health supplement category appeals to three main consumer groups, offering plenty of room for new products, concepts and users. Surprisingly, the fastest-growing group of individuals having knee replacement surgery is not the retirement-age crowd, but those under 50 years old.
Ayurvedic joint health ingredient can impact joint care and show significant impact to the equine market
The manufacturer of a joint health supplement on the human market based on Ayurvedic principles believes new data on its effect on horses will help upend a somewhat sleepy market.
How to market branded ingredients with integrity – podcast
Eric Anderson has been at the forefront of marketing evidence-based, IP-protected ingredients to quality-forward responsible brands. Tune in as Anderson sits down with Insider senior editor Todd Runestad.
Joint health ingredient developer says market overdue for new product backed by solid data
The developer of a new ingredient called TamaFlex said its synergistic pairing of Ayurvedic constituents will help breathe life into the somnolescent joint health category.