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Meet BluNADBooster ® 

Natural, Smarter NAD+ Support

Promote and Preserve NAD+ Levels—Naturally

BluNADBooster® is a patent-pending, clinically studied, plant-based NAD+ longevity ingredient that does what synthetic NAD+ precursors like NR or NMN cannot. Instead of simply adding building blocks, BluNADBooster activates two key biosynthesis pathways and inhibits CD38, the enzyme responsible for age-related NAD+ depletion.

That means:

  • More NAD+ produced.
  • NAD+ levels preserved.
  • Deeper cellular support for energy, vitality, and resilience.

Unlike synthetic precursors, BluNADBooster is entirely natural and herbal, developed to challenge conventional approaches to healthy aging and cellular energy.
It’s not just how much NAD+ you make — it’s how much you keep.

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Promote and Preserve NAD+ Levels—Naturally.

BluNADBooster® is a patent-pending, clinically studied, plant-based NAD+ longevity ingredient that does what synthetic NAD+ precursors like NR or NMN cannot. Instead of simply adding building blocks, BluNADBooster activates two key biosynthesis pathways and inhibits CD38, the enzyme responsible for age-related NAD+ depletion.

That means:

  • More NAD+ produced.
  • NAD+ levels preserved.
  • Deeper cellular support for energy, vitality, and resilience.

Unlike synthetic precursors, BluNADBooster is entirely natural and herbal, developed to challenge conventional approaches to healthy aging and cellular energy.
It’s not just how much NAD+ you make — it’s how much you keep.

BluNADBooster ®  Clinically Validated in Human Study

BluNADBooster has been evaluated through a rigorous, randomized, double-blind, placebo-controlled study involving 140 participants. This pivotal trial was designed to assess the impact of BluNADBooster alone, in combination with NR, and compared to placebo.

*Encouraged by the initial findings, a second human clinical study is now in the protocol development phase.

BluNADBooster ®  Clinically Validated in Human Study

BluNADBooster has been evaluated through a rigorous, randomized, double-blind, placebo-controlled study involving 140 participants. This pivotal trial was designed to assess the impact of BluNADBooster alone, in combination with NR, and compared to placebo.

*Encouraged by the initial findings, a second human clinical study is now in the protocol development phase.

The Next Generation of NAD+ Supplement Ingredients

Next-Level Support: Inside the Innovation

  • Natural, not synthetic: A plant-based alternative to NR and NMN, BluNADBooster supports the body’s own NAD+ production—naturally and safely.

  • Dual-pathway activation: Stimulates both the Salvage and Preiss-Handler pathways to restore NAD+ across multiple systems, including brain, muscle, and metabolic function.

  • CD38 inhibition: Helps preserve NAD+ by inhibiting its breakdown—supporting energy production, immune balance, and cellular repair.

  • Clinically validated and safe: Human clinical study completed; second trial in development.

  • Flexible usage: Use alone or with precursors like NR for synergistic NAD+ support.

Natural Activation. Smarter Preservation. Elevate Cellular Vitality with BluNADBooster®.

The Next Generation of NAD+ Supplement Ingredients

Next-Level Support: Inside the Innovation

  • Natural, not synthetic: A plant-based alternative to NR and NMN, BluNADBooster supports the body’s own NAD+ production—naturally and safely.

  • Dual-pathway activation: Stimulates both the Salvage and Preiss-Handler pathways to restore NAD+ across multiple systems, including brain, muscle, and metabolic function.

  • CD38 inhibition: Helps preserve NAD+ by inhibiting its breakdown—supporting energy production, immune balance, and cellular repair.

  • Clinically validated and safe: Human clinical study completed; second trial in development.

  • Flexible usage: Use alone or with precursors like NR for synergistic NAD+ support.

Natural Activation. Smarter Preservation. Elevate Cellular Vitality with BluNADBooster®.

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Beyond Boosting: A Dual Approach to NAD+ Health

BluNADBooster® supports optimal NAD+ levels through two synergistic mechanisms: activating NAD+ biosynthesis and slowing NAD+ degradation.

Activating Two NAD+ Biosynthesis Pathways

Activating Two NAD+ Biosynthesis Pathways

Most NAD+ boosters only stimulate the Salvage Pathway. BluNADBooster uniquely activates both key biosynthetic routes:

  • Salvage Pathway (via NamPRT): Converts nicotinamide (Vitamin B3) back into NAD+, recycling this essential molecule.
  • Preiss-Handler Pathway (via NAPRT): Utilizes nicotinic acid (niacin) to create NAD+, an often overlooked but critical pathway for whole-body NAD+ replenishment.

By enhancing both pathways simultaneously, BluNADBooster maximizes the body’s natural ability to sustain NAD+ levels.

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Slowing NAD+ Degradation: Inhibiting CD38

Beyond Boosting: A Dual Approach to NAD+ Health

BluNADBooster® supports optimal NAD+ levels through two synergistic mechanisms: activating NAD+ biosynthesis and slowing NAD+ degradation.

1) Activating Two NAD+ Biosynthesis Pathways

Most NAD+ boosters only stimulate the Salvage Pathway. BluNADBooster uniquely activates both key biosynthetic routes:

  • Salvage Pathway (via NamPRT): Converts nicotinamide (Vitamin B3) back into NAD+, recycling this essential molecule.
  • Preiss-Handler Pathway (via NAPRT): Utilizes nicotinic acid (niacin) to create NAD+, an often overlooked but critical pathway for whole-body NAD+ replenishment.

By enhancing both pathways simultaneously, BluNADBooster maximizes the body’s natural ability to sustain NAD+ levels.

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2) Slowing NAD+ Degradation: Inhibiting CD38

CD38 activity increases with age and immune system activation, particularly in immune cells. NAD+ depletion is accelerated by CD38, an enzyme that consumes NAD+ during immune and stress-related responses.

BluNADBooster addresses this hidden barrier by naturally inhibiting CD38 activity, preserving NAD+ stores for vital cellular processes such as energy production, DNA repair, and resilience under stress.

This dual-action mechanism of enhancing production and minimizing loss positions BluNADBooster as a superior approach to comprehensive NAD+ optimization.

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BluNADBooster ® vs. Traditional NAD+ Precursors

BluNADBooster not only activates two major NAD+ pathways but also inhibits CD38, in a natural, safe way, offering broader support than NR or NMN alone. For even greater benefits, BluNADBooster can be combined with NAD+ Precursors to maximize NAD+ optimization.

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BluNADBooster ® vs. Traditional NAD+ Precursors

 

BluNADBooster not only activates two major NAD+ pathways but also inhibits CD38, in a natural, safe way, offering broader support than NR or NMN alone. For even greater benefits, BluNADBooster can be combined with NAD+ Precursors to maximize NAD+ optimization.

BluNadBooster
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Plant Power Meets Precision Science

BluNADBooster is crafted from standardized botanical extracts, selected from over 900 screened candidates for their superior biological activity. Because it is 100% natural and non-synthetic, BluNADBooster also offers excellent safety for long-term use, supporting balance rather than forcing unnatural metabolic spikes.

Hero Botanicals:

  • Pomegranate Extract: Rich in polyphenols that promote NAD+ activation and protect against oxidative stress.
  • Marigold Flower (Tagetes erecta): Source of natural lutein compounds supporting mitochondrial and inflammatory balance.

All ingredients are standardized, clinically defined, and manufactured in cGMP-certified facilities.

Plant Power Meets Precision Science

BluNADBooster is crafted from standardized botanical extracts, selected from over 900 screened candidates for their superior biological activity. Because it is 100% natural and non-synthetic, BluNADBooster also offers excellent safety for long-term use, supporting balance rather than forcing unnatural metabolic spikes.

Hero Botanicals:

  • Pomegranate Extract: Rich in polyphenols that promote NAD+ activation and protect against oxidative stress.
  • Marigold Flower (Tagetes erecta): Source of natural lutein compounds supporting mitochondrial and inflammatory balance.

All ingredients are standardized, clinically defined, and manufactured in cGMP-certified facilities.

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 Versatile, Clinically Supported, and Ready for Innovation

BluNADBooster delivers flexible, science-backed solutions for innovation-driven brands. Its versatile format integrates easily into applications like healthy aging, brain health, energy metabolism, and immune support.

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Tablets

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Capsules

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Gummies

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Powder

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Food

 Versatile, Clinically Supported, and Ready for Innovation

BluNADBooster delivers flexible, science-backed solutions for innovation-driven brands. Its versatile format integrates easily into applications like healthy aging, brain health, energy metabolism, and immune support.

Tablets

Capsules

Gummies

Powder

Food

Learn Why NAD+ Is Central to Health and Aging

NAD+ (Nicotinamide Adenine Dinucleotide) is a vital molecule found in every human cell. It powers energy production, DNA repair, metabolic balance, and brain function.

Yet by the age 40 begins to decline, which can impact fatigue, age-related symptoms, and cellular aging

Understanding how NAD+ works—and why preserving it is critical—is key to unlocking better aging, stronger cells, and enhanced performance.

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Learn Why NAD+ Is Central to Health and Aging

NAD+ (Nicotinamide Adenine Dinucleotide) is a vital molecule found in every human cell. It powers energy production, DNA repair, metabolic balance, and brain function.

Yet by the age 40, NAD+ begins to decline, which can impact fatigue, age-related symptoms, and cellular aging

Understanding how NAD+ works—and why preserving it is critical—is key to unlocking better aging, stronger cells, and enhanced performance.

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BluNADBooster ® News

News

BluNAD Booster

NAD+ supplement review: Science, ingredients and formulation insights

For formulators, pairing a preservation-focused ingredient like BluNADBooster with a traditional precursor could be a way to create additive benefits.

BluNAD Booster

Ingredient suppliers, supplement brands bet big on longevity

Suppliers are introducing ingredients that tackle longevity from both cellular and experiential angles—and brands are tapping into NAD+ ingredients.

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Research Spotlights CD38 Inhibition as a Strategy for NAD+ Preservation

Emerging science is shifting attention from simply raising NAD+ levels toward preserving them, and botanical approaches targeting the CD38 enzyme are at the center of that discussion.

BluNAD Booster

Blue Helix Health to Present New Research on NAD at FASEB Conference

New research highlights that ingredients that preserve existing NAD+ in the body may be just as important as ingredient which boost its production.

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Shakes & Shots Shape Functional Nutrition for Longevity

BluNAD Booster is the first healthy aging and longevity ingredient to target the CD38 enzyme and works synergistically with NAD+ precursors NR and NMN.

BluNAD Booster

New Directions in Longevity and Digestive Health

Check out botanical ingredients targeting NAD metabolism for longevity and GLP-1 digestive support products.

Natural Activation & Smarter Preservation

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Natural Activation & Smarter Preservation